Saline Enema for Constipation

Medically reviewed by a licensed pharmacist · Last reviewed 6/14/2026

Dose

1 enema (118mL) rectally as needed, retain 2-5 minutes before evacuating. Max 1 dose per day unless directed by physician. May cause cramping or urgency.

What to watch for

  • Renal impairment
  • Electrolyte disorder

Not recommended in pregnancy — check with a pharmacist or your clinician first.

Not for children under 2.

Sources

  • FDA OTC Monograph

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Data sources & limitations

Where to buy

This page is for general education and is not medical advice. It does not replace a consultation with a licensed pharmacist or your clinician. Always read and follow the product label. If symptoms are severe, worsening, or persistent, seek professional care.

Saline Enema for Constipation: Uses, Dosing & What to Watch For | Pharmacy360 — Pharmacy360