Best OTC Medicines for Eye
Common over-the-counter options for eye, with typical adult dosing and key safety notes.
Medically reviewed by a licensed pharmacist · Last reviewed
Reviewed against: FDA OTC Monograph
Artificial Tears Cmc
1-2 drops in affected eye(s) as needed. For children under 3 years, consult a doctor before use.
Artificial Tears Hpmc
1-2 drops in affected eye(s) as needed. For adults and children 3 years and older. Do not touch dropper tip to eye or any surface.
Artificial Tears Peg Propylene
1-2 drops in affected eye(s) as needed. Use products containing polyethylene glycol 0.2-1% and/or propylene glycol 0.2-1% per FDA monograph.
Hypertonic Saline 5pct
1-2 drops in affected eye(s) as needed for temporary relief. Do not use for more than 72 hours unless directed by a doctor.
Ketotifen
1 drop in each affected eye twice daily (every 8-12 hours). Allow 5 minutes between drops if using more than one eye drop. Remove contact lenses before use; wait 10 minutes before re-inserting.
Lubricant Ointment Nighttime
Apply a small amount to the inside of the lower eyelid as needed for dry eyes. May cause temporary blurred vision after application.
Naphazoline Pheniramine
1-2 drops in each affected eye up to 4 times daily. Limit to 3-4 days of continuous use to avoid rebound redness. Remove contact lenses before use.
Olopatadine Ophthalmic
1-2 drops in affected eye(s) twice daily, 6-8 hours apart. Remove contact lenses before use; wait 10 minutes before reinserting.
Preservative Free Lubricant
1-2 drops in each affected eye as needed, up to every hour. Single-use vials; do not save unused product (open vials are sterile only on first use).
Tetrahydrozoline Ophthalmic
1-2 drops of 0.05% solution in affected eye(s) up to 4 times daily. Do not use for more than 3 days to avoid rebound redness.
This page is for general education and is not medical advice. It does not replace a consultation with a licensed pharmacist or your clinician. Always read and follow the product label. If symptoms are severe, worsening, or persistent, seek professional care.