Omeprazole for Heartburn

Medically reviewed by a licensed pharmacist · Last reviewed 5/23/2026

Dose

20mg by mouth once daily, taken 30-60 minutes before breakfast. Course is 14 days max without medical advice. Full effect builds over 1-4 days.

What to watch for

  • Clopidogrel concomitant use
  • Rilpivirine concomitant use

Not recommended in pregnancy — check with a pharmacist or your clinician first.

Not for children under 18.

Sources

  • FDA OTC Monograph
  • American College of Obstetricians and Gynecologists

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

Data sources & limitations

Where to buy

This page is for general education and is not medical advice. It does not replace a consultation with a licensed pharmacist or your clinician. Always read and follow the product label. If symptoms are severe, worsening, or persistent, seek professional care.

Omeprazole for Heartburn: Uses, Dosing & What to Watch For | Pharmacy360 — Pharmacy360