Diphenhydramine Oral for Skin
Medically reviewed by a licensed pharmacist · Last reviewed 5/23/2026
Dose
25-50mg by mouth every 4-6 hours as needed for itch. Max 300mg/day. Causes drowsiness — avoid driving.
What to watch for
- Narrow angle glaucoma
- Severe bph
- Maoi use within 14 days
Not for children under 6.
Sources
- FDA OTC Monograph
- American College of Obstetricians and Gynecologists
Where to buy
This page is for general education and is not medical advice. It does not replace a consultation with a licensed pharmacist or your clinician. Always read and follow the product label. If symptoms are severe, worsening, or persistent, seek professional care.